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BIKE
May be involved in osteoblast differentiation. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: BIKE subfamily; EC 2.7.11.1; Kinase, protein; NAK family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of human Ortholog: 4q21.21 |
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Cellular Component:
cytoplasm; nuclear speck; nucleus
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Molecular Function:
AP-2 adaptor complex binding; ATP binding; phosphatase regulator activity; protein serine kinase activity; protein serine/threonine kinase activity
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Biological Process:
positive regulation of Notch signaling pathway; protein phosphorylation; regulation of bone mineralization; regulation of clathrin-dependent endocytosis
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Reference #:
Q9NSY1
(UniProtKB)
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Alt. Names/Synonyms: BIKE; BMP-2-inducible protein kinase; BMP2 inducible kinase; BMP2K; DKFZp434K0614; DKFZp434P0116; HRIHFB2017
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Gene Symbols: BMP2K
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Molecular weight:
129,172 Da
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Basal Isoelectric point:
6.05
Predict pI for various phosphorylation states
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