KRTAP10-3 In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 10 family. Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component:  cytosol; keratin filament
Biological Process:  keratinization
Reference #:  P60369 (UniProtKB)
Alt. Names/Synonyms: High sulfur keratin-associated protein 10.3; KAP10.3; KAP18-3; KAP18.3; keratin associated protein 10-3; Keratin-associated protein 10-3; Keratin-associated protein 10.3; Keratin-associated protein 18-3; Keratin-associated protein 18.3; KR103; KRTAP10-3; KRTAP10.3; KRTAP18-3; KRTAP18.3
Gene Symbols: KRTAP10-3
Molecular weight: 22,348 Da
Basal Isoelectric point: 7.99  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene