ANTXR2 Necessary for cellular interactions with laminin and the extracellular matrix. Belongs to the ATR family. Expressed in prostate, thymus, ovary, testis, pancreas, colon, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, skeletal muscle, small intestine and spleen. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of human Ortholog: 4q21.21
Cellular Component:  cell surface; endoplasmic reticulum membrane; endosome membrane; extracellular region; plasma membrane
Molecular Function:  metal ion binding; protein binding; transmembrane signaling receptor activity
Disease: Hyaline Fibromatosis Syndrome
Reference #:  P58335 (UniProtKB)
Alt. Names/Synonyms: Anthrax toxin receptor 2; ANTR2; ANTXR cell adhesion molecule 2; ANTXR2; Capillary morphogenesis gene 2 protein; capillary morphogenesis protein 2; CMG-2; CMG2; HFS; ISH; JHF
Gene Symbols: ANTXR2
Molecular weight: 53,666 Da
Basal Isoelectric point: 7.42  Predict pI for various phosphorylation states
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ANTXR2
Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein