Lamin B1 Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Belongs to the intermediate filament family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 18q12.1
Cellular Component:  cytoplasm; intermediate filament; lamin filament; nuclear envelope; nuclear inner membrane; nuclear lamina; nuclear matrix; nuclear membrane; nucleoplasm; nucleus
Molecular Function:  double-stranded DNA binding; phospholipase binding; protein binding; sequence-specific double-stranded DNA binding; structural molecule activity
Biological Process:  apoptotic process; cellular response to corticosterone stimulus; cellular response to monosodium L-glutamate; cellular response to organic cyclic compound; neurogenesis; response to antibiotic; response to drug
Reference #:  P70615 (UniProtKB)
Alt. Names/Synonyms: lamin B1; Lamin-B1; Lmnb1
Gene Symbols: Lmnb1
Molecular weight: 66,606 Da
Basal Isoelectric point: 5.16  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Lamin B1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene