SLC30A9 Acts as a zinc transporter involved in intracellular zinc homeostasis. Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. Ubiquitously expressed in fetal and adult tissues and cancer cell lines. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Nuclear receptor co-regulator; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 4p13
Cellular Component:  cytoplasmic vesicle; cytoskeleton; endoplasmic reticulum; integral component of membrane; nucleus
Molecular Function:  cation transmembrane transporter activity; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process:  cation transmembrane transport; cellular zinc ion homeostasis; nucleotide-excision repair; zinc ion transport
Disease: Birk-landau-perez Syndrome
Reference #:  Q6PML9 (UniProtKB)
Alt. Names/Synonyms: BILAPES; C4orf1; expressed in human embryonic lung; GAC63; GRIP1-dependent nuclear receptor coactivator; HUEL; Human embryonic lung protein; SLC30A9; solute carrier family 30 (zinc transporter), member 9; Solute carrier family 30 member 9; Zinc transporter 9; ZnT-9; ZNT9
Gene Symbols: SLC30A9
Molecular weight: 63,515 Da
Basal Isoelectric point: 8.6  Predict pI for various phosphorylation states
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SLC30A9

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  NURSA  |  InnateDB