GPBP1 Functions as a GC-rich promoter-specific transactivating transcription factor. Belongs to the vasculin family. Widely expressed. Some isoforms may be specifically expressed in veins and arteries (at protein level). Isoform 4 is widely expressed. Isoform 1, isoform 2 and isoform 3 may be specifically expressed in vascular smooth muscle cells. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 13|13 D2.2
Cellular Component:  cytosol; intracellular membrane-bounded organelle; nucleus; plasma membrane
Molecular Function:  DNA binding; DNA-binding transcription factor activity; protein binding
Biological Process:  positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated
Reference #:  Q6NXH3 (UniProtKB)
Alt. Names/Synonyms: 1700034P14Rik; AU019836; D230035M11Rik; GC-rich promoter binding protein 1; GC-rich promoter-binding protein 1; Gpbp; Gpbp1; mGPBP; OTTMUSP00000021328; Vasculin
Gene Symbols: Gpbp1
Molecular weight: 53,423 Da
Basal Isoelectric point: 6.43  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene