SLC25A46
May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission. Belongs to the mitochondrial carrier (TC 2.A.29) family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family |
Chromosomal Location of human Ortholog: 5q22.1 |
Cellular Component:
mitochondrial outer membrane; mitochondrion
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Molecular Function:
protein binding; protein-containing complex binding
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Biological Process:
autophagy of mitochondrion; axon development; cerebellar Purkinje cell differentiation; cristae formation; dendrite development; locomotion involved in locomotory behavior; mitochondrial fission; mitochondrial membrane fission; mitochondrial transport; myelination in peripheral nervous system; optic nerve development; peripheral nervous system neuron axonogenesis; phospholipid homeostasis; protein-containing complex assembly; respiratory chain complex IV assembly; synapse assembly
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Disease: Neuropathy, Hereditary Motor And Sensory, Type Vib; Pontocerebellar Hypoplasia, Type 1e
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Reference #:
Q96AG3
(UniProtKB)
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Alt. Names/Synonyms: HMSN6B; Mitochondrial outer membrane protein SLC25A46; S2546; SLC25A46; Solute carrier family 25 member 46; solute carrier family 25, member 46; TB1
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Gene Symbols: SLC25A46
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Molecular weight:
46,174 Da
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Basal Isoelectric point:
6.97
Predict pI for various phosphorylation states
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