ZDHHC1 Belongs to the DHHC palmitoyltransferase family. Expressed at high levels in fetal lung, kidney and heart. Expressed at lower levels in adult pancreas and lung. Note: This description may include information from UniProtKB.
Protein type: EC 2.3.1.225; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of human Ortholog: 16q22.1
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; Golgi apparatus
Molecular Function:  DNA binding; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoyltransferase activity
Biological Process:  antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; positive regulation of defense response to virus by host; protein palmitoylation; protein targeting to membrane
Reference #:  Q8WTX9 (UniProtKB)
Alt. Names/Synonyms: C16orf1; DHHC domain-containing cysteine-rich protein 1; DHHC-1; DHHC-domain-containing cysteine-rich protein; HSU90653; Palmitoyltransferase ZDHHC1; Probable palmitoyltransferase ZDHHC1; ZDHC1; ZDHHC1; Zinc finger DHHC domain-containing protein 1; zinc finger DHHC-type containing 1; Zinc finger protein 377; zinc finger, DHHC domain containing 1; zinc finger, DHHC-type containing 1; ZNF377
Gene Symbols: ZDHHC1
Molecular weight: 54,818 Da
Basal Isoelectric point: 10.35  Predict pI for various phosphorylation states
Select Structure to View Below

ZDHHC1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein