PPCDC Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine. Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 4.1.1.36; Lyase
Chromosomal Location of Human Ortholog: 15q24.2
Cellular Component:  cytosol
Molecular Function:  identical protein binding; phosphopantothenoylcysteine decarboxylase activity; protein binding
Biological Process:  coenzyme A biosynthetic process; coenzyme biosynthetic process
Reference #:  Q96CD2 (UniProtKB)
Alt. Names/Synonyms: COAC; FLJ14585; MDS018; Phosphopantothenoylcysteine decarboxylase; PPC-DC; PPCDC
Gene Symbols: PPCDC
Molecular weight: 22,395 Da
Basal Isoelectric point: 5.72  Predict pI for various phosphorylation states
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PPCDC

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB