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TUBB2A
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. High expression in brain, where it represents 30% of all beta-tubulins. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of human Ortholog: 6p25.2 |
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Cellular Component:
cytoplasm; intercellular bridge; microtubule; microtubule cytoskeleton; mitotic spindle
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Molecular Function:
GTP binding; GTPase activity; metal ion binding; protein binding; structural constituent of cytoskeleton
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Biological Process:
cerebral cortex development; microtubule cytoskeleton organization; mitotic cell cycle; neuron migration
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Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 5
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Reference #:
Q13885
(UniProtKB)
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Alt. Names/Synonyms: CDCBM5; class IIa beta-tubulin; dJ40E16.7; TBB2A; TUBB; TUBB2; TUBB2A; tubulin beta 2A class IIa; Tubulin beta class IIa; Tubulin beta-2A chain; tubulin, beta 2A; tubulin, beta polypeptide 2
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Gene Symbols: TUBB2A
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Molecular weight:
49,907 Da
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Basal Isoelectric point:
4.78
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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