AXUD1 Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. Belongs to the AXUD1 family. Ubiquitous. Most abundantly expressed in lung, placenta, skeletal muscle, pancreas and leukocyte. Frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 3p22.2
Cellular Component:  nucleus
Molecular Function:  DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; sequence-specific DNA binding
Biological Process:  apoptotic process; face morphogenesis; platelet-derived growth factor receptor signaling pathway; positive regulation of transcription by RNA polymerase II; post-embryonic development; roof of mouth development; skeletal system morphogenesis
Reference #:  Q96S65 (UniProtKB)
Alt. Names/Synonyms: Axin-1 up-regulated gene 1 protein; AXIN1 up-regulated 1; AXUD1; CSRN1; CSRNP-1; CSRNP1; cysteine and serine rich nuclear protein 1; cysteine-serine-rich nuclear protein 1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; FAM130B; Protein URAX1; TAIP-3; TAIP3; TGF-beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3; URAX1
Gene Symbols: CSRNP1
Molecular weight: 63,508 Da
Basal Isoelectric point: 4.61  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene