ACP1 Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity. Belongs to the low molecular weight phosphotyrosine protein phosphatase family. T-lymphocytes express only isoform 2. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cofactor and Vitamin Metabolism - riboflavin; EC; EC; Motility/polarity/chemotaxis; Phosphatase (non-protein); Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 6q16
Cellular Component:  cytoplasm; cytoplasmic side of plasma membrane; cytosol; neuron projection; sarcolemma
Molecular Function:  acid phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity; phosphatase activity; protein tyrosine phosphatase activity; SH3 domain binding
Biological Process:  chemical synaptic transmission; peptidyl-tyrosine dephosphorylation
Reference #:  P41498 (UniProtKB)
Alt. Names/Synonyms: acid phosphatase 1, soluble; Acp1; LMW-PTP; LMW-PTP-I low molecular weight phosphotyrosine protein phosphatase isozyme 1; LMW-PTPase; Low molecular weight cytosolic acid phosphatase; Low molecular weight phosphotyrosine protein phosphatase; PPAC
Gene Symbols: Acp1
Molecular weight: 18,152 Da
Basal Isoelectric point: 6.08  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene