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IGSF21
Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. Note: This description may include information from UniProtKB.
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| Protein type: Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 1p36.13 |
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Cellular Component:
adherens junction; external side of plasma membrane; inhibitory synapse; postsynaptic membrane; presynaptic membrane
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Biological Process:
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; synapse maturation
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Reference #:
Q96ID5
(UniProtKB)
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Alt. Names/Synonyms: FLJ41177; IGS21; IgSF21; immunoglobin superfamily member 21; immunoglobin superfamily, member 21; Immunoglobulin superfamily member 21; MGC15730; OTTHUMP00000002532
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Gene Symbols: IGSF21
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Molecular weight:
51,835 Da
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Basal Isoelectric point:
6.48
Predict pI for various phosphorylation states
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