XAB2 Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. Belongs to the crooked-neck family. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; Spliceosome
Chromosomal Location of human Ortholog: 19p13.2
Cellular Component:  catalytic step 2 spliceosome; nucleoplasm; nucleus; U2-type catalytic step 2 spliceosome
Molecular Function:  protein binding
Biological Process:  blastocyst development; cerebral cortex development; mRNA splicing, via spliceosome; transcription, DNA-templated; transcription-coupled nucleotide-excision repair
Reference #:  Q9HCS7 (UniProtKB)
Alt. Names/Synonyms: crn-related protein kim1; DKFZp762C1015; HCNP; HCRN; KIAA1177; NTC90; Pre-mRNA-splicing factor SYF1; Protein HCNP; SYF1; SYF1 homolog, RNA splicing factor; SYF1 pre-mRNA-splicing factor; XAB2; XPA binding protein 2; XPA-binding protein 2
Gene Symbols: XAB2
Molecular weight: 100,010 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB