PRP4 Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: CMGC group; DYRK family; EC 2.7.11.1; Kinase, protein; PRP4 subfamily; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); RNA splicing; Spliceosome
Chromosomal Location of Human Ortholog: 17p12
Cellular Component:  catalytic step 2 spliceosome; chromosome; nuclear speck; nucleus
Molecular Function:  ATP binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process:  mRNA processing; protein phosphorylation; RNA splicing
Reference #:  Q5RKH1 (UniProtKB)
Alt. Names/Synonyms: PRP4; PRP4 pre-mRNA processing factor 4 homolog B (yeast); PRP4 pre-mRNA-processing factor 4 homolog; PRP4B; Prpf4b; Serine/threonine-protein kinase PRP4 homolog
Gene Symbols: Prpf4b
Molecular weight: 117,007 Da
Basal Isoelectric point: 10.23  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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PRP4

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene