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Telethonin
Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk. Heart and skeletal muscle. Note: This description may include information from UniProtKB.
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| Protein type: Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 11|11 D |
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Cellular Component:
cytoplasm; I band; titin-telethonin complex; Z disc
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Molecular Function:
BMP binding; FATZ binding; molecular adaptor activity; protein binding; protein-macromolecule adaptor activity; structural constituent of muscle; titin binding; titin Z domain binding; transmembrane transporter binding
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Biological Process:
adult heart development; cardiac muscle cell development; cardiac muscle contraction; cardiac muscle hypertrophy; cardiac muscle hypertrophy in response to stress; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; detection of muscle stretch; otic vesicle formation; sarcomere organization; sarcomerogenesis; skeletal muscle contraction; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; somitogenesis
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Reference #:
O70548
(UniProtKB)
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Alt. Names/Synonyms: AI503981; AJ223855; OTTMUSP00000002542; Tcap; Telet; Telethonin; TELT; Titin cap protein; titin-cap
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Gene Symbols: Tcap
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Molecular weight:
19,078 Da
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Basal Isoelectric point:
5.73
Predict pI for various phosphorylation states
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