Telethonin Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk. Heart and skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of mouse Ortholog: 11|11 D
Cellular Component:  cytoplasm; I band; Z disc
Molecular Function:  BMP binding; FATZ binding; ion channel binding; protein binding; protein binding, bridging; structural constituent of muscle; titin binding; titin Z domain binding
Biological Process:  adult heart development; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle hypertrophy in response to stress; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; detection of muscle stretch; otic vesicle formation; sarcomere organization; sarcomerogenesis; skeletal muscle contraction; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; somitogenesis
Reference #:  O70548 (UniProtKB)
Alt. Names/Synonyms: AI503981; AJ223855; OTTMUSP00000002542; Tcap; Telet; Telethonin; TELT; Titin cap protein; titin-cap
Gene Symbols: Tcap
Molecular weight: 19,078 Da
Basal Isoelectric point: 5.73  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene