Telethonin Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk. Heart and skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of mouse Ortholog: 11|11 D
Cellular Component:  cytoplasm; I band; titin-telethonin complex; Z disc
Molecular Function:  BMP binding; FATZ binding; molecular adaptor activity; protein binding; protein-macromolecule adaptor activity; structural constituent of muscle; titin binding; titin Z domain binding; transmembrane transporter binding
Biological Process:  adult heart development; cardiac muscle cell development; cardiac muscle contraction; cardiac muscle hypertrophy; cardiac muscle hypertrophy in response to stress; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; detection of muscle stretch; otic vesicle formation; sarcomere organization; sarcomerogenesis; skeletal muscle contraction; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; somitogenesis
Reference #:  O70548 (UniProtKB)
Alt. Names/Synonyms: AI503981; AJ223855; OTTMUSP00000002542; Tcap; Telet; Telethonin; TELT; Titin cap protein; titin-cap
Gene Symbols: Tcap
Molecular weight: 19,078 Da
Basal Isoelectric point: 5.73  Predict pI for various phosphorylation states
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Telethonin

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein