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PLEKHA4
Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. Highly expressed in melanoma. Detected at low levels in heart, skeletal muscle, kidney, liver and small intestine. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of rat Ortholog: 1q22 |
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Cellular Component:
cytoplasm; membrane
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Molecular Function:
phosphatidylinositol-3-phosphate binding
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Reference #:
P60669
(UniProtKB)
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Alt. Names/Synonyms: MGC72599; PEPP-1; Pepp1; PH domain-containing family A member 4; Phosphoinositol 3-phosphate-binding protein 1; PKHA4; pleckstrin homology domain containing family A member 4; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4; Pleckstrin homology domain-containing family A member 4; Plekha4
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Gene Symbols: Plekha4
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Molecular weight:
85,642 Da
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Basal Isoelectric point:
10.21
Predict pI for various phosphorylation states
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