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MAP1A
Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements. Belongs to the MAP1 family. Brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of Human Ortholog: 3q35 |
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Cellular Component:
axon; axon initial segment; cell projection; cytoplasm; cytosol; dendrite; dendritic branch; dendritic microtubule; dendritic shaft; microtubule; microtubule associated complex; neuron projection; neuronal cell body; photoreceptor outer segment; postsynaptic density; primary dendrite; synapse
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Molecular Function:
actin binding; collagen binding; cytoskeletal adaptor activity; ionotropic glutamate receptor binding; microtubule binding; protein binding; tubulin binding
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Biological Process:
anterograde axonal protein transport; associative learning; axonogenesis; dendrite development; memory; microtubule cytoskeleton organization; negative regulation of microtubule depolymerization; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein localization to microtubule; neuron cellular homeostasis; neuron projection maintenance; photoreceptor cell maintenance; positive regulation of cellular protein localization; positive regulation of protein localization to cell surface; regulation of microtubule depolymerization; regulation of synaptic plasticity; retrograde axonal protein transport; sensory perception of sound; voluntary musculoskeletal movement
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Reference #:
P34926
(UniProtKB)
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Alt. Names/Synonyms: MAP-1A; MAP1 light chain LC2; Map1a; Microtubule-associated protein 1A; Mtap1a
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Gene Symbols: Map1a
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Molecular weight:
299,531 Da
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Basal Isoelectric point:
4.87
Predict pI for various phosphorylation states
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