MAP1A Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements. Belongs to the MAP1 family. Brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3q35
Cellular Component:  axon; axon initial segment; cell projection; cytoplasm; cytosol; dendrite; dendritic branch; dendritic microtubule; dendritic shaft; microtubule; microtubule associated complex; neuron projection; neuronal cell body; photoreceptor outer segment; postsynaptic density; primary dendrite; synapse
Molecular Function:  actin binding; collagen binding; cytoskeletal adaptor activity; ionotropic glutamate receptor binding; microtubule binding; protein binding; tubulin binding
Biological Process:  anterograde axonal protein transport; associative learning; axonogenesis; dendrite development; memory; microtubule cytoskeleton organization; negative regulation of microtubule depolymerization; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein localization to microtubule; neuron cellular homeostasis; neuron projection maintenance; photoreceptor cell maintenance; positive regulation of cellular protein localization; positive regulation of protein localization to cell surface; regulation of microtubule depolymerization; regulation of synaptic plasticity; retrograde axonal protein transport; sensory perception of sound; voluntary musculoskeletal movement
Reference #:  P34926 (UniProtKB)
Alt. Names/Synonyms: MAP-1A; MAP1 light chain LC2; Map1a; Microtubule-associated protein 1A; Mtap1a
Gene Symbols: Map1a
Molecular weight: 299,531 Da
Basal Isoelectric point: 4.87  Predict pI for various phosphorylation states
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MAP1A

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene