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TCFL5
Putative transcription factor. Isoform 3 may play a role in early spermatogenesis. Isoform 3 is testis specific. Isoform 2 is pancreas specific. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding |
| Chromosomal Location of human Ortholog: 20q13.33 |
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Cellular Component:
chromatin; male germ cell nucleus; nucleus
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Molecular Function:
DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding
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Biological Process:
cell differentiation; negative regulation of transcription by RNA polymerase II; regulation of cell differentiation; regulation of cell population proliferation; regulation of DNA-templated transcription; spermatogenesis; transcription by RNA polymerase II
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Reference #:
Q9UL49
(UniProtKB)
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Alt. Names/Synonyms: bHLHe82; CHA; Cha transcription factor; E2BP-1; E2BP1; Figlb; HPV-16 E2 binding protein 1; HPV-16 E2-binding protein 1; MGC46135; SOSF1; spermatogenesis- and oogenesis-specific bHLH-containing protein 1; TCFL5; transcription factor like 5; transcription factor-like 5 (basic helix-loop-helix); Transcription factor-like 5 protein
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Gene Symbols: TCFL5
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Molecular weight:
52,697 Da
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Basal Isoelectric point:
6.44
Predict pI for various phosphorylation states
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