NUP37 Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. Note: This description may include information from UniProtKB.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 12q23.2
Cellular Component:  condensed chromosome kinetochore; cytosol; host cell; nuclear envelope; nuclear pore outer ring; nucleoplasm
Molecular Function:  protein binding
Biological Process:  cell cycle; cell division; chromosome segregation; intracellular transport of virus; mRNA export from nucleus; protein sumoylation; regulation of cellular response to heat; regulation of gene silencing by miRNA; regulation of glycolytic process; tRNA export from nucleus; viral process; viral transcription
Disease: Microcephaly 24, Primary, Autosomal Recessive
Reference #:  Q8NFH4 (UniProtKB)
Alt. Names/Synonyms: FLJ22618; MGC5585; nucleoporin 37kDa; Nucleoporin Nup37; Nup107-160 subcomplex subunit Nup37; NUP37; p37
Gene Symbols: NUP37
Molecular weight: 36,708 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene