S6 May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Belongs to the eukaryotic ribosomal protein eS6 family. Note: This description may include information from UniProtKB.
Protein type: Translation
Chromosomal Location of Human Ortholog: 5q32
Cellular Component:  cell body; cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; cytosolic small ribosomal subunit; dendrite; endoplasmic reticulum; nucleolus; nucleus; perinuclear region of cytoplasm; polysome; ribonucleoprotein complex; ribosome; small ribosomal subunit
Molecular Function:  mRNA binding; protein kinase binding; structural constituent of ribosome
Biological Process:  activation-induced cell death of T cells; cellular response to ethanol; cellular response to insulin-like growth factor stimulus; erythrocyte development; G1/S transition of mitotic cell cycle; gastrulation; glucose homeostasis; mammalian oogenesis stage; mitotic cell cycle; mitotic cell cycle checkpoint; negative regulation of apoptotic process; negative regulation of bicellular tight junction assembly; placenta development; positive regulation of apoptotic process; response to insulin; ribosomal small subunit assembly; ribosomal small subunit biogenesis; rRNA processing; T cell differentiation in thymus; T cell proliferation involved in immune response; TOR signaling; translation
Reference #:  P62755 (UniProtKB)
Alt. Names/Synonyms: 40S ribosomal protein S6; ribosomal protein S6; Rps6; RS6; S6
Gene Symbols: Rps6
Molecular weight: 28,681 Da
Basal Isoelectric point: 10.85  Predict pI for various phosphorylation states
CST Pathways:  Growth And Differentiation Control by MAPKs  |  PI3K/Akt Signaling  |  Translation: eIF4E and p70S6K
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene