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CIDEB
Activates apoptosis. Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen. Note: This description may include information from UniProtKB.
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| Protein type: Apoptosis |
| Chromosomal Location of human Ortholog: 14q12 |
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Cellular Component:
COPI-coated vesicle; COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; lipid droplet; perinuclear region of cytoplasm
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Molecular Function:
identical protein binding; lipid transfer activity; molecular adaptor activity; phosphatidic acid binding; protein binding
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Biological Process:
activation of cysteine-type endopeptidase activity; apoptotic process; bile acid signaling pathway; COPII-coated vesicle cargo loading; execution phase of apoptosis; intermembrane lipid transfer; intrinsic apoptotic signaling pathway in response to DNA damage; lipid droplet fusion; lipid storage; positive regulation of release of cytochrome c from mitochondria; regulation of apoptotic process; regulation of triglyceride metabolic process; response to nutrient levels; very-low-density lipoprotein particle assembly
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Reference #:
Q9UHD4
(UniProtKB)
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Alt. Names/Synonyms: Cell death activator CIDE-B; cell death inducing DFFA like effector b; Cell death-inducing DFFA-like effector B; CIDEB; Lipid transferase CIDEB
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Gene Symbols: CIDEB
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Molecular weight:
24,678 Da
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Basal Isoelectric point:
9.01
Predict pI for various phosphorylation states
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