SNX19 Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). Belongs to the sorting nexin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 11q24.3-q25
Cellular Component:  cytoplasm; cytoplasmic vesicle membrane; early endosome membrane
Molecular Function:  phosphatidylinositol-3-phosphate binding; protein binding
Biological Process:  chondrocyte differentiation; dense core granule maturation; exocytosis; insulin secretion
Reference #:  Q92543 (UniProtKB)
Alt. Names/Synonyms: CHET8; DKFZp667I205; KIAA0254; SNX19; sorting nexin 19; Sorting nexin-19
Gene Symbols: SNX19
Molecular weight: 108,598 Da
Basal Isoelectric point: 4.97  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene