DIXDC1 Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2. Belongs to the DIXDC1 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Cell development/differentiation
Chromosomal Location of Human Ortholog: 11q23.1
Cellular Component:  cytoskeleton; cytosol; focal adhesion
Molecular Function:  actin binding; gamma-tubulin binding; protein binding; protein domain specific binding
Biological Process:  canonical Wnt signaling pathway; cerebral cortex radially oriented cell migration; forebrain ventricular zone progenitor cell division; negative regulation of neuron differentiation; positive regulation of Wnt signaling pathway; regulation of actin cytoskeleton organization; regulation of microtubule cytoskeleton organization
Reference #:  Q155Q3 (UniProtKB)
Alt. Names/Synonyms: CCD1; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain containing 1; DIX domain-containing protein 1; DIXC1; DIXDC1; Dixin; KIAA1735
Gene Symbols: DIXDC1
Molecular weight: 77,478 Da
Basal Isoelectric point: 5.85  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein