PRND Required for normal acrosome reaction and for normal male fertility. Can bind Cu(2+). Belongs to the prion family. Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level). Note: This description may include information from UniProtKB.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of human Ortholog: 20p13
Cellular Component:  external side of plasma membrane; extracellular region; plasma membrane
Molecular Function:  copper ion binding; protein binding
Biological Process:  acrosome reaction; cellular copper ion homeostasis; protein homooligomerization
Reference #:  Q9UKY0 (UniProtKB)
Alt. Names/Synonyms: dJ1068H6.4; DOPPEL; downstream prion protein-like; DPL; MGC41841; prion gene complex, downstream; prion like protein doppel; Prion protein 2; prion protein 2 (dublet); Prion-like protein doppel; PRND; PrPLP
Gene Symbols: PRND
Molecular weight: 20,293 Da
Basal Isoelectric point: 9.24  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene