ARHGAP25
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: GAP; GAP, Rac/Rho |
Chromosomal Location of mouse Ortholog: 6|6 D1 |
Cellular Component:
phagocytic cup
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Molecular Function:
GTPase activator activity
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Biological Process:
actin filament organization; activation of GTPase activity; negative regulation of small GTPase mediated signal transduction; phagocytosis, engulfment; signal transduction
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Reference #:
Q8BYW1
(UniProtKB)
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Alt. Names/Synonyms: A130039I20Rik; Arhgap25; Kiaa0053; OTTMUSP00000026601; OTTMUSP00000026603; RHG25; Rho GTPase activating protein 25; Rho GTPase-activating protein 25; Rho-type GTPase-activating protein 25
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Gene Symbols: Arhgap25
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Molecular weight:
73,383 Da
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Basal Isoelectric point:
6.03
Predict pI for various phosphorylation states
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