FABP2 FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. Note: This description may include information from UniProtKB.
Protein type: Lipid-binding; Transporter
Chromosomal Location of mouse Ortholog: 3 G1|3 53.74 cM
Cellular Component:  apical cortex; cytoplasm; cytosol; intracellular anatomical structure; microvillus; nucleus; plasma membrane
Molecular Function:  fatty acid binding; lipid binding; long-chain fatty acid binding; long-chain fatty acid transporter activity
Biological Process:  fatty acid metabolic process; fatty acid transport; intestinal absorption; intestinal lipid absorption; long-chain fatty acid transport
Reference #:  P55050 (UniProtKB)
Alt. Names/Synonyms: Fabp2; Fabpi; fatty acid binding protein 2, intestinal; fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein, intestinal; I-F; I-FABP; intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein
Gene Symbols: Fabp2
Molecular weight: 15,126 Da
Basal Isoelectric point: 6.62  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene