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SERPINA6
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Belongs to the serpin family. Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. Note: This description may include information from UniProtKB.
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| Protein type: Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 14q32.13 |
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Cellular Component:
extracellular region; extracellular space
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Molecular Function:
serine-type endopeptidase inhibitor activity; steroid binding
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Biological Process:
glucocorticoid metabolic process; negative regulation of endopeptidase activity
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Disease: Corticosteroid-binding Globulin Deficiency
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Reference #:
P08185
(UniProtKB)
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Alt. Names/Synonyms: CBG; corticosteroid binding globulin; Corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6; Serpin A6; serpin family A member 6; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6; SERPINA6; Transcortin
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Gene Symbols: SERPINA6
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Molecular weight:
45,141 Da
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Basal Isoelectric point:
5.64
Predict pI for various phosphorylation states
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