SERPINA6 Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Belongs to the serpin family. Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 14q32.13
Cellular Component:  extracellular region; extracellular space
Molecular Function:  serine-type endopeptidase inhibitor activity; steroid binding
Biological Process:  glucocorticoid metabolic process; negative regulation of endopeptidase activity
Disease: Corticosteroid-binding Globulin Deficiency
Reference #:  P08185 (UniProtKB)
Alt. Names/Synonyms: CBG; corticosteroid binding globulin; Corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6; Serpin A6; serpin family A member 6; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6; SERPINA6; Transcortin
Gene Symbols: SERPINA6
Molecular weight: 45,141 Da
Basal Isoelectric point: 5.64  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB