THY1 May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component:  apical plasma membrane; axolemma; cell surface; cytosol; dendrite membrane; endoplasmic reticulum; external side of plasma membrane; extracellular region; growth cone; integral component of plasma membrane; membrane raft; neuronal cell body membrane; plasma membrane
Molecular Function:  GPI anchor binding; GTPase activator activity; integrin binding; protein binding
Biological Process:  angiogenesis; cell-cell adhesion; cell-cell signaling; cytoskeleton organization; focal adhesion assembly; integrin-mediated signaling pathway; negative regulation of axonogenesis; negative regulation of cell migration; negative regulation of neuron projection regeneration; negative regulation of protein kinase activity; negative regulation of protein tyrosine kinase activity; negative regulation of T cell receptor signaling pathway; positive regulation of cellular extravasation; positive regulation of focal adhesion assembly; positive regulation of GTPase activity; positive regulation of heterotypic cell-cell adhesion; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of T cell activation; protein autophosphorylation; receptor clustering; regulation of cell-matrix adhesion; regulation of Rho-dependent protein serine/threonine kinase activity; retinal cone cell development; T cell receptor signaling pathway
Reference #:  P04216 (UniProtKB)
Alt. Names/Synonyms: CD90; CDw90; FLJ33325; Thy-1 antigen; Thy-1 cell surface antigen; Thy-1 membrane glycoprotein; Thy-1 T-cell antigen; THY1
Gene Symbols: THY1
Molecular weight: 17,935 Da
Basal Isoelectric point: 8.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene