NPY
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. Belongs to the NPY family. One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. Note: This description may include information from UniProtKB.
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Protein type: Hormone; Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: 7p15.3 |
Cellular Component:
extracellular region; extracellular space; GABA-ergic synapse; Golgi apparatus; neuronal dense core vesicle
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Molecular Function:
calcium channel regulator activity; G protein-coupled receptor activity; neuropeptide hormone activity; neuropeptide Y receptor binding; protein binding; signaling receptor binding
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Biological Process:
adult feeding behavior; central nervous system neuron development; cerebral cortex development; chemical synaptic transmission; feeding behavior; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; intestinal epithelial cell differentiation; neuron projection development; neuropeptide signaling pathway; positive regulation of appetite; regulation of blood pressure; synaptic signaling via neuropeptide
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Reference #:
P01303
(UniProtKB)
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Alt. Names/Synonyms: C-flanking peptide of NPY; CPON; Neuropeptide tyrosine; Neuropeptide Y; NPY; prepro-neuropeptide Y; Pro-neuropeptide Y; PYY4
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Gene Symbols: NPY
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Molecular weight:
10,851 Da
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Basal Isoelectric point:
6.57
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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