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CRMP-3
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of mouse Ortholog: 7|7 F4 |
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Cellular Component:
cytoplasm; cytosol
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Molecular Function:
filamin binding; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; phosphoprotein binding; protein binding
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Biological Process:
neuron death; neuron projection guidance
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Reference #:
O35098
(UniProtKB)
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Alt. Names/Synonyms: AI173505; Collapsin response mediator protein 3; Crm; CRMP; CRMP-3; Crmp3; dihydropyrimidinase-like 4; Dihydropyrimidinase-related protein 4; DPY; DPY4; DPYL4; Dpysl4; Drp; DRP-4; ULIP-4; Ulip4; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4
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Gene Symbols: Dpysl4
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Molecular weight:
61,962 Da
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Basal Isoelectric point:
6.51
Predict pI for various phosphorylation states
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