ARHGAP28 GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho
Chromosomal Location of Human Ortholog: 18p11.31
Cellular Component:  cytosol
Biological Process:  positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction
Reference #:  Q9P2N2 (UniProtKB)
Alt. Names/Synonyms: ARHGAP28; DKFZp686A2038; FLJ10312; KIAA1314; RHG28; Rho GTPase activating protein 28; Rho GTPase-activating protein 28; Rho-type GTPase-activating protein 28
Gene Symbols: ARHGAP28
Molecular weight: 82,060 Da
Basal Isoelectric point: 7.62  Predict pI for various phosphorylation states
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ARHGAP28

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein