GIPC1
May be involved in G protein-linked signaling. Belongs to the GIPC family. Widely expressed. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: GAP; GAP, misc.; Motility/polarity/chemotaxis; Vesicle |
Chromosomal Location of mouse Ortholog: 8|8 C2 |
Cellular Component:
brush border; cell cortex; cytoplasm; cytoplasmic vesicle; cytosol; dendritic shaft; dendritic spine; endocytic vesicle; glutamatergic synapse; membrane; postsynapse; presynapse; Schaffer collateral - CA1 synapse; synaptic vesicle; vesicle membrane
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Molecular Function:
actin binding; GTPase activator activity; identical protein binding; myosin binding; PDZ domain binding; protein binding; signaling receptor binding
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Biological Process:
cellular response to interleukin-7; chemical synaptic transmission; endothelial cell migration; G protein-coupled receptor signaling pathway; glutamate secretion; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cytokinesis; positive regulation of melanin biosynthetic process; positive regulation of transforming growth factor beta receptor signaling pathway; presynaptic modulation of chemical synaptic transmission; protein targeting; regulation of protein stability; regulation of synaptic plasticity
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Reference #:
Q9Z0G0
(UniProtKB)
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Alt. Names/Synonyms: GAIP C-terminus-interacting protein; Gipc; GIPC PDZ domain containing family, member 1; Gipc1; Glut1; Glut1CIP; neurophilin1-IP; PDZ domain-containing protein GIPC1; regulator of G-protein signaling 19 interacting protein 1; RGS-GAIP interacting protein GIPC; RGS-GAIP-interacting protein; Rgs1; RGS19-interacting protein 1; Rgs19ip1; semaF cytoplasmic domain associated protein; SemaF cytoplasmic domain-associated protein 1; Semc; SEMCAP-1; Semcap1; syne; Synectin; Tax; Tax interacting protein, clone 2; TaxIP2; TIP; TIP-2
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Gene Symbols: Gipc1
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Molecular weight:
36,129 Da
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Basal Isoelectric point:
5.65
Predict pI for various phosphorylation states
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