GPR88
Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function. Belongs to the G-protein coupled receptor 1 family. Expressed predominantly in the striatum. Note: This description may include information from UniProtKB.
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Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
Chromosomal Location of human Ortholog: 1p21.2 |
Cellular Component:
cilium; cytoplasm; nucleus; plasma membrane
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Molecular Function:
cytoskeletal motor activity; G protein-coupled photoreceptor activity
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Biological Process:
cellular response to light stimulus; detection of visible light; G protein-coupled receptor signaling pathway; locomotory behavior; motor learning; neuromuscular process controlling balance; neuronal action potential; phototransduction
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Disease: Chorea, Childhood-onset, With Psychomotor Retardation
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Reference #:
Q9GZN0
(UniProtKB)
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Alt. Names/Synonyms: COCPMR; G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; GPR88; Probable G-protein coupled receptor 88; STRG; Striatum-specific G-protein coupled receptor
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Gene Symbols: GPR88
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Molecular weight:
40,246 Da
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Basal Isoelectric point:
9.8
Predict pI for various phosphorylation states
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