KCTD8 Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 4p13
Cellular Component:  cell projection; postsynaptic membrane; presynaptic membrane; receptor complex
Molecular Function:  protein binding
Biological Process:  protein homooligomerization; regulation of G protein-coupled receptor signaling pathway
Reference #:  Q6ZWB6 (UniProtKB)
Alt. Names/Synonyms: BTB/POZ domain-containing protein KCTD8; KCTD8; potassium channel tetramerisation domain containing 8; potassium channel tetramerization domain containing 8
Gene Symbols: KCTD8
Molecular weight: 52,440 Da
Basal Isoelectric point: 8.6  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB