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KCTD8
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. Note: This description may include information from UniProtKB.
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| Chromosomal Location of human Ortholog: 4p13 |
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Cellular Component:
cell projection; postsynaptic membrane; presynaptic membrane; receptor complex
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Molecular Function:
protein binding
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Biological Process:
protein homooligomerization; regulation of G protein-coupled receptor signaling pathway
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Reference #:
Q6ZWB6
(UniProtKB)
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Alt. Names/Synonyms: BTB/POZ domain-containing protein KCTD8; KCTD8; potassium channel tetramerisation domain containing 8; potassium channel tetramerization domain containing 8
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Gene Symbols: KCTD8
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Molecular weight:
52,440 Da
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Basal Isoelectric point:
8.6
Predict pI for various phosphorylation states
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