|
TG
Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Belongs to the type-B carboxylesterase/lipase family. Thyroid gland specific. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 8q24.22 |
|
Cellular Component:
extracellular region
|
|
Molecular Function:
hormone activity
|
|
Biological Process:
hormone biosynthetic process; iodide transport; regulation of myelination; regulation of signaling receptor activity; signal transduction; thyroid gland development; thyroid hormone metabolic process
|
|
Disease: Autoimmune Thyroid Disease, Susceptibility To, 3; Thyroid Dyshormonogenesis 3
|
|
Reference #:
P01266
(UniProtKB)
|
|
Alt. Names/Synonyms: AITD3; TG; TGN; THYG; Thyroglobulin
|
|
Gene Symbols: TG
|
|
Molecular weight:
304,790 Da
|
|
Basal Isoelectric point:
5.4
Predict pI for various phosphorylation states
|
