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KRTAP5-5
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 5 family. Restricted to hair root, not detected in any other tissues. Note: This description may include information from UniProtKB.
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| Chromosomal Location of human Ortholog: 11p15.5 |
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Cellular Component:
cytosol; keratin filament
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Reference #:
Q701N2
(UniProtKB)
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Alt. Names/Synonyms: KAP5-11; KAP5.5; keratin associated protein 5-11; keratin associated protein 5-5; Keratin-associated protein 5-11; Keratin-associated protein 5-5; Keratin-associated protein 5.11; Keratin-associated protein 5.5; KRA55; KRTAP5-11; KRTAP5-5; KRTAP5.11; KRTAP5.5; OTTHUMP00000063272; Q701N2; Ultrahigh sulfur keratin-associated protein 5.5
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Gene Symbols: KRTAP5-5
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Molecular weight:
21,409 Da
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Basal Isoelectric point:
8.39
Predict pI for various phosphorylation states
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