NFKBID Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR). May also regulate TCR-induced negative selection of thymocytes. Belongs to the NF-kappa-B inhibitor family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 19q13.12
Cellular Component:  nucleus
Molecular Function:  protein binding
Biological Process:  inflammatory response; positive regulation of T-helper 17 cell differentiation; regulation of gene expression; T cell receptor signaling pathway
Reference #:  Q8NI38 (UniProtKB)
Alt. Names/Synonyms: I-kappa-B-delta; IkappaBdelta; IkappaBNS; IkB-delta; IKBD; IKBNS; MGC11314; MGC149503; NF-kappa-B inhibitor delta; NFKB inhibitor delta; NFKBID; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; Q8NI38; T-cell activation NFKB-like protein; TA-NFKBH
Gene Symbols: NFKBID
Molecular weight: 33,481 Da
Basal Isoelectric point: 6.9  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein