TSPAN1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component:  cell junction; cytoplasm; intracellular membrane-bounded organelle; lysosomal membrane; membrane; nucleoplasm; perinuclear region of cytoplasm; plasma membrane; vesicle
Molecular Function:  protein binding
Biological Process:  cell migration; cell proliferation; positive regulation of endocytosis; protein stabilization
Reference #:  O60635 (UniProtKB)
Alt. Names/Synonyms: 9030418M05Rik; NET-1; O60635; OTTHUMP00000008900; RP11-322N21.1; tetraspan 1; tetraspan 1 (TSPAN-1); tetraspan NET-1; tetraspan TM4SF; tetraspanin 1; tetraspanin TM4-C; Tetraspanin-1; TSPAN-1; TSPAN1
Gene Symbols: TSPAN1
Molecular weight: 26,301 Da
Basal Isoelectric point: 5.12  Predict pI for various phosphorylation states
Select Structure to View Below

TSPAN1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein