TSPAN1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component:  cell junction; cytoplasm; intracellular membrane-bounded organelle; lysosomal membrane; membrane; nucleoplasm; perinuclear region of cytoplasm; plasma membrane; vesicle
Molecular Function:  protein binding
Biological Process:  cell migration; cell proliferation; positive regulation of endocytosis; protein stabilization
Reference #:  O60635 (UniProtKB)
Alt. Names/Synonyms: 9030418M05Rik; NET-1; O60635; OTTHUMP00000008900; RP11-322N21.1; tetraspan 1; tetraspan 1 (TSPAN-1); tetraspan NET-1; tetraspan TM4SF; tetraspanin 1; tetraspanin TM4-C; Tetraspanin-1; TSPAN-1; TSPAN1
Gene Symbols: TSPAN1
Molecular weight: 26,301 Da
Basal Isoelectric point: 5.12  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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