UBC3B Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin. Belongs to the ubiquitin-conjugating enzyme family. Note: This description may include information from UniProtKB.
Protein type: EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of mouse Ortholog: 4|4 A5
Cellular Component: 
Molecular Function:  ATP binding; nucleotide binding; transferase activity; ubiquitin conjugating enzyme activity; ubiquitin-protein transferase activity
Biological Process:  protein K48-linked ubiquitination; protein monoubiquitination; protein polyubiquitination; ubiquitin-dependent protein catabolic process
Reference #:  Q6ZWZ2 (UniProtKB)
Alt. Names/Synonyms: 1200003M11Rik; Cdc34b; E2 ubiquitin-conjugating enzyme R2; E2-CDC34B; OTTMUSP00000007008; UB2R2; Ubc3b; Ube2r2; Ubiquitin carrier protein R2; Ubiquitin-conjugating enzyme E2 R2; Ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; Ubiquitin-protein ligase R2
Gene Symbols: Ube2r2
Molecular weight: 27,166 Da
Basal Isoelectric point: 4.26  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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UBC3B

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein