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PEX7
Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. Belongs to the WD repeat peroxin-7 family. Ubiquitous. Highest expression in pancreas, skeletal muscle and heart. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Cellular Component:
cytosol; peroxisomal matrix; peroxisome
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Molecular Function:
enzyme binding; peroxisome matrix targeting signal-2 binding; protein homodimerization activity
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Biological Process:
endochondral ossification; ether lipid biosynthetic process; fatty acid beta-oxidation; neuron migration; peroxisome organization; protein import into peroxisome matrix; protein targeting to peroxisome
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Reference #:
Q498S5
(UniProtKB)
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Alt. Names/Synonyms: peroxisomal biogenesis factor 7; peroxisome biogenesis factor 7
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Gene Symbols: Pex7
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Molecular weight:
35,528 Da
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Basal Isoelectric point:
5.22
Predict pI for various phosphorylation states
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