RNASET2 Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA. Probably plays a role in cellular RNA catabolism. Belongs to the RNase T2 family. Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.27.-; RNA-binding; Ribonuclease; Secreted; Secreted, signal peptide
Cellular Component:  endoplasmic reticulum lumen; extracellular region; extracellular space; lysosomal lumen; lysosome
Molecular Function:  ribonuclease T2 activity; RNA binding; RNA endonuclease activity; RNA nuclease activity
Biological Process:  RNA catabolic process
Reference #:  D3ZCH6 (UniProtKB)
Alt. Names/Synonyms: ribonuclease T2; Rnaset2
Gene Symbols: Rnaset2
Molecular weight: 29,517 Da
Basal Isoelectric point: 5.99  Predict pI for various phosphorylation states
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RNASET2

Protein Structure Not Found.


Cross-references to other databases:  BioGPS  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene