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DPP10
Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. Belongs to the peptidase S9B family. DPPIV subfamily. Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell surface; Membrane protein, integral |
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Cellular Component:
membrane; plasma membrane; voltage-gated potassium channel complex
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Molecular Function:
dipeptidyl-peptidase activity; potassium channel regulator activity; protein binding; serine-type peptidase activity; transmembrane transporter binding
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Biological Process:
positive regulation of protein localization to plasma membrane; protein localization to plasma membrane; proteolysis; regulation of potassium ion transmembrane transport
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Reference #:
Q6Q629
(UniProtKB)
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Alt. Names/Synonyms: Dipeptidyl peptidase X; DPP X; DPP10; Inactive dipeptidyl peptidase 10; Kv4 potassium channel auxiliary subunit
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Gene Symbols: Dpp10
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Molecular weight:
90,891 Da
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Basal Isoelectric point:
6.23
Predict pI for various phosphorylation states
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