DPP10 Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. Belongs to the peptidase S9B family. DPPIV subfamily. Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell surface; Membrane protein, integral
Cellular Component:  membrane; plasma membrane; voltage-gated potassium channel complex
Molecular Function:  dipeptidyl-peptidase activity; potassium channel regulator activity; protein binding; serine-type peptidase activity; transmembrane transporter binding
Biological Process:  positive regulation of protein localization to plasma membrane; protein localization to plasma membrane; proteolysis; regulation of potassium ion transmembrane transport
Reference #:  Q6Q629 (UniProtKB)
Alt. Names/Synonyms: Dipeptidyl peptidase X; DPP X; DPP10; Inactive dipeptidyl peptidase 10; Kv4 potassium channel auxiliary subunit
Gene Symbols: Dpp10
Molecular weight: 90,891 Da
Basal Isoelectric point: 6.23  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  BioGPS  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein