CAPN10
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake. Belongs to the peptidase C2 family. Detected in primary skeletal muscle cells (at protein level). Ubiquitous. 8 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Apoptosis; EC 3.4.22.-; Mitochondrial; Protease |
Cellular Component:
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Reference #:
Q9ES66
(UniProtKB)
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Alt. Names/Synonyms: Calcium-activated neutral proteinase 10; Calpain-10; CAN10; CANP 10
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Gene Symbols: Capn10
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Molecular weight:
74,527 Da
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Basal Isoelectric point:
6.97
Predict pI for various phosphorylation states
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