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COX1
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. Belongs to the heme-copper respiratory oxidase family. Note: This description may include information from UniProtKB.
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| Protein type: EC 1.9.3.1; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Oxidoreductase |
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Cellular Component:
mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV
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Molecular Function:
cytochrome-c oxidase activity; heme binding; metal ion binding
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Biological Process:
cerebellum development; electron transport coupled proton transport; mitochondrial electron transport, cytochrome c to oxygen; positive regulation of vasoconstriction; response to copper ion; response to electrical stimulus; response to oxidative stress
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Reference #:
P05503
(UniProtKB)
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Alt. Names/Synonyms: Coi; COX1; cytochrome c oxidase I, mitochondrial; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; mt-Co1; Mtco1
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Gene Symbols: mt-Co1
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Molecular weight:
56,845 Da
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Basal Isoelectric point:
6.29
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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