ATP2B3 iso5 This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily. Highly expressed in the cerebellum, particulary in the presynaptic terminals of parallel fibers-Purkinje neurons. Isoform XE and isoform XB are the most abundant isoforms and are detected at low levels in brain and fetal skeletal muscle. The other isoforms are only found at lower levels and not in fetal tissues. 8 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.6.3.8; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel
Cellular Component: 
Reference #:  Q16720-5 (UniProtKB)
Alt. Names/Synonyms: AT2B3; ATP2B3; ATP2B3 iso5; ATPase plasma membrane Ca2+ transporting 3; ATPase, Ca++ transporting, plasma membrane 3; CFAP39; cilia and flagella associated protein 39; CLA2; OPCA; plasma membrane calcium ATPase; Plasma membrane calcium ATPase isoform 3; plasma membrane calcium pump; Plasma membrane calcium pump isoform 3; Plasma membrane calcium-transporting ATPase 3; PMCA3; PMCA3a; SCAX1
Gene Symbols: ATP2B3
Molecular weight: 128,110 Da
Basal Isoelectric point: 5.68  Predict pI for various phosphorylation states
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ATP2B3 iso5

Protein Structure Not Found.

Cross-references to other databases:  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene