TAF5L Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Belongs to the WD repeat TAF5 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 1q42.13
Cellular Component:  cytoplasmic ribonucleoprotein granule; nuclear speck; nucleus; STAGA complex; transcription factor TFTC complex
Molecular Function:  protein binding; transcription coactivator activity
Biological Process:  histone H3 acetylation; positive regulation of nucleic acid-templated transcription; transcription by RNA polymerase II
Reference #:  O75529 (UniProtKB)
Alt. Names/Synonyms: PAF65-beta; PAF65B; PCAF associated factor 65 beta; PCAF-associated factor 65 beta; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF5L; TATA-box binding protein associated factor 5 like
Gene Symbols: TAF5L
Molecular weight: 66,155 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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