CDK5R2 Activator of CDK5/TPKII. Belongs to the cyclin-dependent kinase 5 activator family. Brain and neuron specific. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 2q35
Cellular Component:  cytoplasm; growth cone; membrane; neuron projection; plasma membrane; protein kinase 5 complex
Molecular Function:  actin binding; cyclin-dependent protein serine/threonine kinase activator activity; lipid binding
Biological Process:  cerebellum development; hippocampus development; layer formation in cerebral cortex; neuron migration; positive regulation of calcium ion-dependent exocytosis; positive regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of cyclin-dependent protein serine/threonine kinase activity; superior olivary nucleus maturation
Reference #:  Q13319 (UniProtKB)
Alt. Names/Synonyms: CD5R2; CDK5 activator 2; CDK5R2; cyclin dependent kinase 5 regulatory subunit 2; Cyclin-dependent kinase 5 activator 2; cyclin-dependent kinase 5 activator isoform p39i; Cyclin-dependent kinase 5 regulatory subunit 2; cyclin-dependent kinase 5, regulatory subunit 2 (p39); NCK5AI; neuronal CDK5 activator isoform; p39; p39I; p39nck5ai
Gene Symbols: CDK5R2
Molecular weight: 38,705 Da
Basal Isoelectric point: 9.76  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene