Calmodulin
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. Belongs to the calmodulin family. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Protein phosphatase, regulatory subunit
Cellular Component:
Reference #:
Q6YNX6
(UniProtKB)
Alt. Names/Synonyms: CALM; CALM1; CALM2; CALM3; Calmodulin; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2 (phosphorylase kinase, delta); calmodulin 3 (phosphorylase kinase, delta); CaM
Gene Symbols: CALM1; CALM2; CALM3
Molecular weight:
16,838 Da
Basal Isoelectric point:
4.09
Predict pI for various phosphorylation states
CST Pathways:
Actin Dynamics
|
B Cell Receptor Signaling
|
ErbB/HER Signaling
|
T Cell Receptor Signaling
Select Structure to View Below
Calmodulin
1AJI - A=5-148 (human)
1CDL - A/B/C/D=2-148 (human)
1CLL - A=1-149 (human)
1CTR - A=1-149 (human)
1IWQ - A=2-149 (human)
1J7O - A=1-77 (human)
1J7P - A=83-149 (human)
1K90 - D/E/F=2-149 (human)
1K93 - D/E/F=6-149 (human)
1L7Z - A=1-149 (human)
1LVC - D/E/F=1-149 (human)
1NKF - A=94-105 (human)
1PK0 - D/E/F=1-148 (human)
1S26 - D/E/F=1-149 (human)
1SK6 - D/E/F=2-149 (human)
1SW8 - A=1-80 (human)
1UP5 - A/B=1-148 (human)
1WRZ - A=1-149 (human)
1XFU - O/P/Q/R/S/T=1-149 (human)
1XFV - O/P/Q/R/S/T=1-149 (human)
1XFW - O/P/Q/R/S/T=1-149 (human)
1XFX - O/P/Q/R/S/T=1-149 (human)
1XFY - O/P/Q/R/S/T=1-149 (human)
1XFZ - O/P/Q/R/S/T=1-149 (human)
1Y6W - A=1-149 (human)
1YR5 - A=2-149 (human)
1YRT - B=76-149 (human)
1YRU - B=76-149 (human)
1ZOT - B=71-93 (human)
1ZUZ - A=1-149 (human)
2BE6 - A/B/C=1-149 (human)
2F3Y - A=1-149 (human)
2F3Z - A=1-149 (human)
2HF5 - A=47-114 (human)
2I08 - A=3-78 (human)
2JZI - A=2-149 (human)
2K0E - A=2-149 (human)
2K0F - A=2-149 (human)
2K0J - A=3-149 (human)
2K61 - A=2-149 (human)
2KNE - A=2-149 (human)
2KUG - A=2-77 (human)
2KUH - A=83-149 (human)
2L53 - A=2-149 (human)
2LGF - A=4-149 (human)
2LL6 - A=2-149 (human)
2LL7 - A=2-149 (human)
2LQC - A=2-78 (human)
2LQP - A=79-149 (human)
2LV6 - A=2-149 (human)
2M0J - A=2-149 (human)
2M0K - A=2-149 (human)
2M55 - A=2-149 (human)
2MG5 - A=2-149 (human)
2N27 - A=2-149 (human)
2N6A - A=6-147 (human)
2N77 - A=77-149 (human)
2N8J - A=2-149 (human)
2R28 - A/B=1-149 (human)
2V01 - A=1-149 (human)
2V02 - A=1-149 (human)
2VAY - A=4-149 (human)
2W73 - A/B/E/F=1-149 (human)
2WEL - D=1-149 (human)
2X0G - B=2-149 (human)
2Y4V - A=1-149 (human)
3BYA - A=2-149 (human)
3DVE - A=2-149 (human)
3DVJ - A=2-149 (human)
3DVK - A=2-149 (human)
3DVM - A=2-149 (human)
3EWT - A=2-149 (human)
3EWV - A=2-149 (human)
3G43 - A/B/C/D=2-149 (human)
3HR4 - B/D/F/H=1-149 (human)
3J41 - F/E=1-149 (human)
3O77 - A=3-149 (human)
3O78 - A/B=3-149 (human)
3OXQ - A/B/C/D=1-149 (human)
3SUI - A=1-149 (human)
3UCT - A/B=2-80 (human)
3UCW - A/D/C/B=2-80 (human)
3UCY - A=2-80 (human)
4BW7 - A/C=1-149 (human)
4BW8 - A/B=1-149 (human)
4BYF - B/D=1-149 (human)
4DCK - B=1-149 (human)
4DJC - A=1-149 (human)
4GOW - D=4-147 (human)
4JPZ - C/I=1-149 (human)
4JQ0 - C=1-149 (human)
4L79 - B=1-149 (human)
4LZX - A=2-149 (human)
4M1L - A=2-149 (human)
4OVN - A/D/C/E/B=1-149 (human)
4Q57 - A=10-74 (human)
4Q5U - A=1-149 (human)
4UMO - D/C=1-149 (human)
4UPU - A=2-149 (human)
4V0C - D/C=1-149 (human)
5COC - A=5-78 (human)
5DBR - A=5-149 (human)
5DOW - A/C/G/E=2-149 (human)
5DSU - A=3-78 (human)
5GGM - A=2-149 (human)
5I0I - C/E=3-147 G=84-126 I=84-147 (human)
5J03 - B=1-149 (human)
5J8H - A=2-149 (human)
5JQA - A=1-149 (human)
5JTH - A=1-149 (human)
5K7L - B=1-149 (human)
5K8Q - A=1-149 (human)
5NIN - A/B=1-149 (human)
5OEO - A=1-149 (human)
5TP5 - A=2-149 (human)
5TP6 - A=2-149 (human)
5V02 - B=395-486 (human)
5V03 - B=395-486 (human)
5V7X - B=1-149 (human)
5VMS - B=1-149 (human)
5WBX - R=5-148 (human)
5WC5 - R=5-148 (human)
5WSU - A/B=2-149 (human)
5WSV - A/C=1-147 (human)
6B8L - H/F/D/B=1-149 (human)
6B8M - H/F/D/B=1-149 (human)
6B8N - H/F/D/B=1-149 (human)
6B8P - H/F/D/B=1-149 (human)
6B8Q - H/F/D/B=1-149 (human)
6BUT - A=2-149 (human)
6CNM - H/F/G/E=1-149 (human)
6CNN - H/F/G/E=1-149 (human)
6CNO - H/F/G/E=1-149 (human)
6DAD - A/B=2-149 (human)
6DAE - A/B=2-149 (human)
6DAF - A/B=2-149 (human)
6DAH - A/D/C/B=1-149 (human)
6E2F - E=1-149 (human)
6E2G - A/D/C/B=41-767 (human)
6EEB - A=1-149 (human)
6FEG - A=502-532 (human)
6FEH - A=502-532 (human)
6GDK - A=2-149 (human)
6GDL - A=2-149 (human)
6HCS - A/C/G/E=1-149 (human)
6HR1 - A/B=2-149 (human)
6K4K - D/C=1-149 (human)
6K4L - D/C=1-149 (human)
6K4R - D/C=1-149 (human)
6M7H - A=2-148 (human)
6MUD - B=1786-1922 (human)
6MUE - B=1716-1744 (human)
6N5W - C=1-149 (human)
6O5G - A=1-149 (human)
6OS4 - A=2-149 (human)
6PAW - F/A/E/B=12-330 (human)
6PBX - H/F/D/B=1-149 (human)
6PBY - H/F/D/B=1-149 (human)
6PLM - D/C=2-148 (human)
6S5T - B=1-149 (human)
6SZ5 - C/B=19-737 (human)
6U39 - S/A/O/K/E/Q/M/C/I/G=2-149 (human)
6U3A - A/B=2-149 (human)
6U3B - A=2-149 (human)
6U3D - A/B=2-149 (human)
6UZZ - A/C/G/E=76-620 (human)
6V00 - F/C/I/L=1-103 (human)
6V01 - F/C/I/L=1-103 (human)
6XYR - A=2-149 (human)
6Y4O - A=1-149 (human)
6Y4P - A=1-149 (human)
6Y94 - A=2-149 (human)
6Y95 - A=2-149 (human)
6YNS - A/B/C/D/E/F/G/H/I/J/K/L=2-149 (human)
6YNU - A/C=2-149 (human)
6ZBI - B/C=622-657 (human)
7KL5 - B=4246-4275 (human)
2DFS - B/C/D/E/F/G/N/O/P/Q/R/S=1-149 (mouse)
2IX7 - A/B=3-147 (mouse)
3WFN - B/C/D/E=1-149 (mouse)
4E50 - A=1-149 (mouse)
4E53 - A/B=1-149 (mouse)
4HEX - A/B=1-149 (mouse)
4ZLK - B=1-149 (mouse)
7B1G - E=1-149 (mouse)
7CQP - C=785-812 (mouse)
1G4Y - R=2-149 (rat)
1NIW - A/C/E/G=1-149 (rat)
1QX5 - B/D/I/J/K/R/T/Y=1-149 (rat)
1QX7 - A/B/I/M/R=2-149 (rat)
2HQW - A=2-149 (rat)
2MGU - A=2-149 (rat)
2PQ3 - A=2-77 (rat)
2YGG - B=1-149 (rat)
3B32 - A=2-76 (rat)
3BXK - A/C=2-149 (rat)
3BXL - A=2-149 (rat)
3CLN - A=2-149 (rat)
3EK4 - A=3-149 (rat)
3EK7 - A=3-149 (rat)
3EK8 - A=3-149 (rat)
3EKH - A=3-149 (rat)
3EKJ - A=3-149 (rat)
3EVR - A=3-148 (rat)
3EVU - A=3-148 (rat)
3EVV - A=3-148 (rat)
3IFK - A/B=2-91 (rat)
3SG2 - A=3-149 (rat)
3SG3 - A=3-149 (rat)
3SG4 - A=3-149 (rat)
3SG5 - A=3-149 (rat)
3SG6 - A=3-149 (rat)
3SG7 - A=3-149 (rat)
3SJQ - A/B=1-149 (rat)
3WLC - A=3-149 (rat)
3WLD - A=3-149 (rat)
4EHQ - A=2-149 (rat)
4G27 - R=1-149 (rat)
4G28 - R=1-149 (rat)
4I2Y - A/B=3-149 (rat)
4IL1 - A/B/C/D=1-149 (rat)
4J9Y - R=1-149 (rat)
4J9Z - R=1-149 (rat)
4OY4 - A=3-147 (rat)
4QNH - R=1-149 (rat)
4RJD - A/B=83-148 (rat)
6MBA - A=1599-1764 (rat)
6MC9 - A=1599-1754 (rat)
7NQC - A=1-149 (rat)
1AHR - A=1-148 (chicken)
1UP5 - A/B=2-149 (chicken)
2BCX - A=2-149 (chicken)
2BKI - B/D=2-149 (chicken)
2KZ2 - A=77-149 (chicken)
2M3S - A=1-149 (chicken)
2O5G - A=2-149 (chicken)
2O60 - A=2-149 (chicken)
2VB6 - B=1-149 (chicken)
3GOF - A/B=2-149 (chicken)
3GP2 - A=2-148 (chicken)
5HIT - A=2-148 (chicken)
6BNV - S/Q/O/T/R/P=4-148 (chicken)
1A29 - A=1-149 (cow)
1AK8 - A=1-76 (cow)
1CDM - A=5-148 (cow)
1CM1 - A=2-149 (cow)
1CM4 - A/C/E/G=2-149 (cow)
1CMF - A=77-149 (cow)
1CMG - A=77-149 (cow)
1DEG - A=6-148 (cow)
1FW4 - A=79-149 (cow)
1LIN - A=1-149 (cow)
1PRW - A=1-149 (cow)
1QIV - A=1-149 (cow)
1QIW - A/B=1-149 (cow)
1XA5 - A=1-149 (cow)
2CLN - A=1-149 (cow)
2F2O - A/B=0-148 (cow)
2F2P - A/B=0-148 (cow)
2FOT - A=2-149 (cow)
3IF7 - A=2-149 (cow)
6O20 - F=1-149 (cow)
