MGAM May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. Belongs to the glycosyl hydrolase 31 family. Expressed in small intestine, granulocyte, and kidney but not in salivary gland or pancreas. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - starch and sucrose; EC; EC; Hydrolase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7q34
Cellular Component:  apical plasma membrane; ficolin-1-rich granule membrane; integral component of membrane; plasma membrane; tertiary granule membrane
Molecular Function:  alpha-1,4-glucosidase activity; amylase activity; carbohydrate binding; catalytic activity; glucan 1,4-alpha-glucosidase activity; maltose alpha-glucosidase activity
Biological Process:  maltose metabolic process; neutrophil degranulation; polysaccharide digestion; starch catabolic process
Reference #:  O43451 (UniProtKB)
Alt. Names/Synonyms: Alpha-glucosidase; brush border hydrolase; Glucan 1,4-alpha-glucosidase; Glucoamylase; Maltase; maltase-glucoamylase; maltase-glucoamylase (alpha-glucosidase); Maltase-glucoamylase, intestinal; MG; MGA; MGAM; MGAML
Gene Symbols: MGAM
Molecular weight: 209,852 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene